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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11161df0b01f15fd088f5c5b465dceec08fede848de12af19eca8ece03a7b99d' 
  AND token = 'cny/sseRfpS6DC1rLt7OvUlfPSdTaiTdCz6JxjbVZZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}