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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65876a001d670a0e1301f9c662380cfba61a01bdf03eb90e0c31b2c6d8a9e30e' 
  AND token = 'Rs2owHziNoK4JUmNtzKGyTRrh6CmU04Q9qJtMhfnPQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}