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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb4b7c83538acfe43733dff9c720de8a2646ebd84dbf28722e654a97fc8aeea8' 
  AND token = 'EfFjxzW+W7J2oY4rvV5oBo+f9LlGC2SE+lBOg40s8yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}