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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5531a60a3b3277db238af0e52f31f9e2e257808bd104188514c5c440737e523' 
  AND token = '/TwGwD9VmLb66uZMR3ieVaHpfYS/3IKiXF0rKeXEAE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}