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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6aad65b1f633b019d3ccac002b589d81179889814cc099dbfd25a58888e5be6' 
  AND token = '45kUdueOzti0nCWYksqVAF1az4U3hCcC2bzANJr/V5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}