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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861ef7a087ad0480fce8eebe396b5e80e9a98e175ab152adae8c094fd27d3587' 
  AND token = 'NKB9tmDWSCq9ao8YMAwVL8N1e0giYK6oGikn6ZF9vkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}