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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad9c5968dec81a2abde4bd0b4b2425635dcadf149951c6153b8e7129e385f4c' 
  AND token = '2/z3SanwhzUByPhox0CIkCFyZ3TM9yPRkQhr9fDJHcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}