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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a88290b6bbbdbac3cfa1a121e9dc5d06c9055cea72e7f566caaa042079a4c5d' 
  AND token = 'Pmo8GfEFg0CUx8qX8N3bvMaPYq0reNpQdEFAInMG0uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}