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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea244ef4cc88aa08f69d278754927dd63493af5a2b12c3d42ebbb59ed0c32685' 
  AND token = 'wZB75Rcxkywibi5BTINtS3O0Xs3MZXTL2JFLOyYFbz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}