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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fc788298920b35e627cd54ab5b84de0aba949d74b9c934c4dd56affb08bd45' 
  AND token = 'gJGjt9TW60gs7RMjgyCWPbEfCtR+gcs6PeieD9VtVnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}