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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e633791721b2050e3c36e4694860c845c6e2158c799c6cad3cd8e387bf9e1b' 
  AND token = '193p3Qy96auku7x/NiTQBUWVicpOGodf07h5roMFO0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}