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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8354a1f0e22ec916e46aa53eea55fc2a47cc8aba09baca384d75f9a62bb0690' 
  AND token = 'x6KKLXxCCrPOe6UYb33lAJMbCWBrCPdQieW+u30Qil4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}