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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b1c254567662ebddeee4f097c3b50ab4335331677fbd4f05a256a8d8f612da' 
  AND token = 'qCQyfaC6ASnbrLVEbwW0kwowEh80s6vKpjT962N/iBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}