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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd486c8cf0f31018fc65dd05afc3c72f91ca23d29a3f0f881beb69349414ec35b' 
  AND token = 'fS/l3AxU71r2Aaj67Oxg44RtNqCE9AcSt4lXb6NlbZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}