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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5e6e1df09c18de7e32438fb5d951195f185c25d2834296c2b15127bff728282' 
  AND token = 'NGT6q+SzrbaMVe8rKGknoc0SozGjKQ2KeCA2cA9FqNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}