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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7427ddaae918c4839533f1de8a2afdb3ab328d090bd5ace01091cff868771ce' 
  AND token = '6SByi0UCpX3EsuNL6SsPTFofww6mSwrm8PO0XWvfRMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}