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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb48722ad6204156622d9d48b6769c3f10f10aaf83d26755bcef004d4596a503' 
  AND token = 'MFOX2t7nd+BUdeX++1Ak0MqvdON2FWURWelSulRxtxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}