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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c856370973049f7f66ad0f0d107855958c8aeb2a4f5b016d3792d4981361d8' 
  AND token = 'Ij6eUI2YkkIo3OZTOVtCZeiN3tLFF41EQ2QZhmyPP/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}