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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22aa4e40f6c224daa8411b94b754d57229ac24a774608e2c24d17c9309751b03' 
  AND token = 'M4t4gPQBr0uS9RVfAUlEr/b5pRmE9h8yEzOhS0SIZMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}