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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41183a6c7a5518502b108252275a4e518d9f8ecee93e1e674a331c71e14cca11' 
  AND token = 'zbPyfZM4K2q0yn3Zpnvjz6l4paxSKzhK46k6rCQIk78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}