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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a551d100b68c8d677276e2406ca8bf1efb7369a02b53d60179e016b2856d61' 
  AND token = 'UVWRMe6+7MFsFXr+G3yu7PSitPo2EqnFvD+rO5b7pXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}