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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da8b3d2758b91e9a661dc6849265731082bc33752bfeab6b095e8245bc82a77' 
  AND token = 'txCO74jLyOOK/JOTsqk3Fi6UmO0jX0Rk/UR1CpukGcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}