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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb81af6efb48b0fc689a7fb99c448da0828a6fd1df17d6b9d63a6b9f723ac9c' 
  AND token = 'MuExa0OCMmZpEVKBx5id/3hUDuXnsZ1LxjuuuNoV6E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}