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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d487a5aacda60c91da967e378fc0f781f425cce009736839e44b2b411a54eab' 
  AND token = '1bSzfD7ERh5QIM/52DAwVkwCYGTa3z6ysSbjBS8FK4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}