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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b3ab959a5ee04181eaf10b35ebb80c897f4164f02f481c707c0e6ce05df3c6' 
  AND token = 'dJmVm+q9rKu/TE4xQmbiHNeoP8GaFfSgzUU6eGHrAjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}