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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8857c26fc68972731bb48da91a0d4323db8f79b969d9bdad8fd7e1d3ba4f799' 
  AND token = 'iWZAB6b8VGmSob9zeVU6WS9JOPYtntwK1Y4kr2avHIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}