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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de5a7319195eb66f91126fb911bd610f629ee2e0410460071c744d51df794c4' 
  AND token = '9PpSsy6UqqC+sTVvPWxiGI4OCXgXHUHTM8g8Lvlb9II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}