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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2908ba45e0a0f2a69c02d8c3e89c54a6169db735fbeba0da27d9dab79d1341df' 
  AND token = 't57vABSeJYZ8v8EOu4J4LIqShu6lLYTmjnIv26+fEdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}