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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdb4be19e1b9d83279e83c3ad4868a41fbb7b0542ec3294664ea15f0399b6e48' 
  AND token = 'ZrmPs0i5u7VNZ8jL7W4eVmen/VIHsNrbT2wib+Noz+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}