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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ba44ae37a39d219a7da6bb7702c41ba4e62e61f19988b155434ffa6fc0bf8c' 
  AND token = 'JXtrZM0rKmHgl7AbwhBG4H5+oN9c4w+Z3+pQT2Z4dpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}