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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95f2237e7b3ec3dacf62e32a10216965fe78aedf883a971007a3c160659bb5f' 
  AND token = 'z39jxD3KZOxou0F7O1+qZZtae5jlsReY3qYfc6HO/tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}