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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef0cfa0615e64c4f0e9180e7c2d4df4954d8f755aa61ee757d492739677f6408' 
  AND token = 'J+Gcmyf4CxNrtb+VsO8aFzwUrBSn9hZKoiMhBHV6q0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}