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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f77fcfb7bc2433a550e6106adb3723df9067c30c3597d0b6149007bd0a9fe4' 
  AND token = 'wlVVZSzB5eIwLadsfeQlF6vy+xGgnkR+tJ89+nZc4XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}