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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80ac7308a5afe6c4f89d39cfc85a0beec17d10cf05b1212b7cb16999400345b' 
  AND token = 'W9hovbHft5XLV4jnagY8mZbWBZKdP7Q745y8pQGWsh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}