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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852b8c35faceb1b3ae50afc73ace39b273b19486c4c37f9ac34cd92aba48feff' 
  AND token = 'Hs5vwL9Q+YXu+FOqcgALdPR4QGbUWTl1UntGl+nawis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}