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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4610c76f054a3065cd898a87c612fbe05d7d533d038a444628d23e2711c065fb' 
  AND token = 'gQeIUQOJU26DpCGBJmkYlRIvTDBLj1l8MvcT1K2k2ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}