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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d0c30f3e5367271a402f9439139eac4d57e7cc901dabe388ab8dcb88022050' 
  AND token = 'mNadTvYcQkCxceexqqbOlueL6ldcfnAsQN59e/k7NDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}