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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc71bc7fa0e87986dd26dd625f64b45b48c98a97436d89ce54f347485fd4a278' 
  AND token = '4X3dS50+sr/CtRaOXK8rByC2cdZ8eZS2SBpRE7O7RAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}