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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d1c133b2056b266d98b5d35b746c12784a6c95e95e24315a86e8932bc11c8e' 
  AND token = 'N2cLpw3RadHJ+OU6NUbpebSFRqiePZ6sFs/GEdc17B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}