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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fabc13b01e6208c46f1c76741a6a4aade86b3297e42fbd9091b32d09a057f0' 
  AND token = 'lM2GHp4VNZusjqf0Cuz+faJF3ETlSiVIRuut/nfP0Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}