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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5973c82a9f3220988298eba6ab1d4ee23efeeeba94881bdbbdda7836c1808330' 
  AND token = 'sYiEPzhs6yGKDrCRMYzoHSymnVJuVhw+WVFVAsT+yNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}