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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561c4e3e8d3999e5647911db6e4d25d075b3c7533297854315911587880c8fef' 
  AND token = 'i13dOdxSsx/AHGSSaq2wbMlloZmP4vPx0kOUswIFuFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}