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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ca5c590fa7f3cd79b35aa45d6ce73eec94f536397a9117e2e94bdd20449a47' 
  AND token = 'Eemay6xcDF7z0I4ILbvdmPBB0hkdt+1kQ2eS/pH0szM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}