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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29c70b9a871f73315251d5b2409506f0a9170a79716344fb754d92ad1cec2b78' 
  AND token = '1u7OJNZnuSVGOd9Wt2lASbkEeGGcvS1FskTxgoo+ZC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}