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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4baa6689fb1f7285090846f5af23f1188a6edd53e4d8238c8bd7ddea1be9b95' 
  AND token = 'YiNvxgeTfN2MVYISl+mR0fAwq9rDkioyiHMZh6w6aMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}