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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c36c4cd7e4d35dffe234253cf63f0f0e4634770b86cf9c6500ead50350ce9aa4' 
  AND token = 'D8zdBhifRLZACoRID2ALPee7K/kUHsVkaSwJ8QfwUjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}