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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e409e1d4a37d78f60cae922b97f28df08d766e3fb63e953dad735b157b6bf8' 
  AND token = 'in1b6LTAw1Jsev/JTYY/i5N0RgjMa1Yv22kSSrnhotk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}