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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6669642dee07941d1cfbbfed24a0568e1acf8d6b9a069897afd112d85ad1344' 
  AND token = 'bRIyRhxm4L1/1nCnSJ7kpxkiuATqTMdRdqJScAst2mI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}