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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c96cee1405ff1ad32d9455a7c49865644e666e50a511087adab0f28b18758075' 
  AND token = '+/RbWebfMGd8xtBfsWR4wpyFmGWqpJVMwEpeRv4470I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}