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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a8e7d46c28741fe32be2d883622f83d14c1e9055c8cb5f0e04e146b575232e6' 
  AND token = '1XNc5x2V2o2aHja8PI0cfN/rG0HKVDel8712RydmdLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}